Stiff Person Syndrome

Symptoms include muscle spasms hyper-rigidity debilitating pain and chronic anxiety. Stiff person syndrome SPS is a very rare disease affecting only one or two people per million.

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It causes progressive muscle stiffness and painful spasms that can be triggered by a variety of things including sudden movement cold temperature or unexpected loud noises.

. A small minority of patients have. Stiff person syndrome is more likely seen in people with certain types of diseases including. SPS occurs in about one in a million people and is most commonly found in middle-aged people.

Muscle rigidity sporadic muscle spasms and chronic muscle pain characterize SPS. Stiff person syndrome SPS is a rare autoimmune neurological disorder. Chronic pain impaired mobility and lumbar hyperlordosis are common symptoms.

Myoclonus is a general term used to describe the sudden involuntary jerking of a muscle or group of muscles caused by muscle contractions positive myoclonus or muscle relaxation negative myoclonus. Symptoms may include extreme muscle stiffness rigidity and painful spasms in the trunk and limbs severely impairing mobility. Stiff person syndrome SPS is a rare progressive syndrome that affects the nervous system specifically the brain and spinal cord.

Stiff-person syndrome SPS is a rare neurological disorder with features of an autoimmune disease. SPS is labeled as a rare disease. Certain cancers including breast lung kidney thyroid colon and Hodgkins lymphoma.

Symptoms include muscle spasms and rigidity. Affected individuals also develop involvement of the brainstem which can cause myoclonus. Stiff-person syndrome also known as stiff-man syndrome is a rare neurologic disorder of unclear cause characterized by progressive rigidity and stiffness.

Muscle spasms can be so violent they can dislocate joints and even break bones. Autoimmune disorders including diabetes thyroiditis vitiligo and pernicious anemia. The cause of this extremely rare disease is still unknown.

SPS is strongly correlated with autoimmune diseases and it is usual to find high titers of antibodies against acid decarboxylase GAD65. SPS is characterized by fluctuating muscle rigidity in the trunk and limbs and a heightened sensitivity to stimuli such as noise touch and emotional distress which can set off muscle spasms. Learn more about the treatment and outlook for the condition here.

But more people are affected than reported due to misdiagnoses. Stiff Person Syndrome SPS is an autoimmune and neurological disorder that can make the muscles in the torso and limbs alternate between rigidity and spasms. Stiff person syndrome SPS is a neurological disease with autoimmune features.

Jerking stiff-person syndrome is characterized by muscles stiffness and spasms usually affecting the legs. Spasms can generate enough force to fracture bone. Stiff-person syndrome SPS is a rare and disabling central nervous system disorder with no satisfactory treatment.

The stiffness primarily affects the truncal muscles and is superimposed by spasms resulting in postural deformities.

New Center For Stiff Person Syndrome Johns Hopkins Medicine